Abstract:

Objective To analyze the features and risk factors of early postoperative on right ventricular dysfunction（RVD） in pneumonectomy for lung cancer. Methods A total of 97 lung cancer patients who received pneumonectomy from March 2007 to September 2010 were included in the study. The patients were assigned into RVD group（Tei＞0.28）and normal group（Tei≤0.28）， and postoperative factors were collected and analyzed between two groups， and the multivariate analysis（Logistic regression） were use to identify the risk factors of RVD. ResultsNo one died during hospitalization. The incidence rate of RVD was 16.5％（16／97）. Univariate analysis revealed that there were significant differences in age， FEV1/FVC, preoperative arrhythmias， preoperative pulmonary function， pulmonary hypertension， right pneumonectomy and volume overload between two groups（P＜0.05）. Three variables were found to be significantly related to the development of RVD by multivariate analysis： age（OR=12.68，P＜0.01）， pulmonary hypertension（OR=8.31，P＜0.05）， volume overload（OR=15.74，P＜0.01）. Conclusion RVD is a serious complication after pneumonectomy. Factors such as age＞70 years，pulmonary hypertension and volume overload are associated with RVD.