临床肿瘤学杂志
• 综述与讲座 • 上一篇 下一篇
于万涛1,王朝霞2
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YU Wantao, WANG Zhaoxia.
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摘要: miR-100既可表现出致癌基因的作用,又可表现出抑癌基因的作用,其不仅在多种肿瘤(宫颈癌、前列腺癌、膀胱癌和肺癌等)的发生、发展中发挥重要作用,而且还可增加肿瘤细胞对化疗药物的敏感性。miR-100有望成为肿瘤治疗的新靶点及预测预后的新分子标记。本文结合国内外最新报道对miR-100与肿瘤相关性的研究进展作一综述。
Abstract: Recent studies have shown that miR-100 can act as oncogene or tumor suppressor gene in different tumors. It not only plays an important role in the development and progression of a variety of tumor types(cervical cancer, prostate cancer, bladder cancer, lung cancer, etc), but also can resensitize tumor cell towards chemotherapeutic drugs. miR-100 is expected to become a new target for cancer treatment and a new molecular marker for prognostic predictors. In this review, we summarize the latest progresses, both domestic and overseas, in the roles of miR-100 in the tumor development.
于万涛1,王朝霞2. miR-100与肿瘤关系的研究进展[J]. 临床肿瘤学杂志, 2014, 19(8): 747-.
YU Wantao, WANG Zhaoxia.. Research progress on miR-100 and tumor[J]. Chinese Clinical Oncology, 2014, 19(8): 747-.
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http://manu65.magtech.com.cn/Jwk3_lczlxzz/CN/Y2014/V19/I8/747
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