临床肿瘤学杂志

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循环microRNA在肺癌研究中的进展

刘凤珍,王朝霞   

  1. 210011 南京南京医科大学第二附属医院肿瘤科
  • 收稿日期:2013-09-26 修回日期:2014-02-14 出版日期:2014-10-30 发布日期:2014-10-30
  • 通讯作者: 王朝霞

Progression of circulating microRNA in lung cancer

LIU Fengzhen, WANG Zhaoxia.   

  1. Department of Oncology, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, China
  • Received:2013-09-26 Revised:2014-02-14 Online:2014-10-30 Published:2014-10-30
  • Contact: WANG Zhaoxia

摘要: microRNA(miRNA)在肺癌的发生、发展中发挥着重要的调控作用。循环miRNA的发现,为肺癌诊断、治疗及预后判断提供了一种潜在的非侵入性生物标志。本文结合国内外最新报道对循环miRNA在肺癌诊断、预后判断及铂类化疗敏感性预测等方面的研究进展作一综述。

Abstract: MicroRNAs(miRNAs) play an important regulating role in the occurrence and development of lung cancer. And the finding of circulating miRNAs provides potential noninvasive biomarkers for the diagnosis, treatment and prognosis judgment of lung cancer. In this review, we summarized the research progress of circulating miRNAs as a valuable biomarker for the diagnosis, prognosis and platinum-based chemotherapy sensitivity of lung cancer from the latest articles home and abroad.

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