Abstract:

Objective To investigate the factors influencing sentinel lymph node metastasis（SLNM）in primary breast cancer. Methods The clinical data of 264 female primary breast cancer patients in Shunyi Health Care Hospital for Women and Children from Jan 2008 to Dec 2014 were retrospectively reviewed. The relationship between SLNM and clinicopathological features was analyzed. Results SLNM was found in 59 cases among 264 breast cancer patients. Tumor size，ER status and HER-2 status were significantly associated with SLNM in univariate analysis（P＜0.05）. Tumor size and HER-2 status were independent factors influencing SLNM in unconditional logistic regression analysis（P＜0.05）. Conclusion Tumor size and HER-2 status were independent factors influencing SLNM. Further study was needed to investigate the association between SLNM and other clinicopathological features.