Abstract: Objective To investigate the prognostic factors of survival for gastric neuroendocrine carcinoma. Methods The clinicopathological and follow-up data of 42 patients with gastric neuroendocrine carcinoma, who were diagnosed by surgical resection and pathology from May 2006 to July 2011, were analyzed retrospectively. The survival was estimated using Kaplan-Meier method and compared using logrank test. The effectiveness of independent factors on prognosis was determined by Cox regression multivariate analysis. Results All the 38 patients were followed up. The median survival of these 38 patients was 25 months，and the overall 1-，3-and 5-year survival rates were 71.1％，26.3％ and 15.8％，respectively. Univariate and multivariate analysis showed that clinical stage，maximum tumor diameter and surgical procedure were independent prognostic factors of gastric neuroendocrine carcinoma，while gender and age were not significantly correlated with prognosis. Conclusion Clinical stage，maximum tumor diameter and surgical procedure are main prognostic factors for gastric neuroendocrine carcinoma. Early diagnosis and radical resection are effective ways to prolong the postoperative survival in patients with gastric neuroendocrine carcinoma.