Chinese Clinical Oncology

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Follow-up analysis of surgical treatment for patients with metastatic carcinoma in the pelvis

YANG Yongkun, NIU Xiaohui, LIU Weifeng, JIN Tao, HUANG Zhen.
  

  1. Department of Orthopaedic Oncology, Jishuitan Hospital, Beijing 100035, China
  • Received:2013-12-16 Revised:2014-01-22 Online:2014-06-30 Published:2014-06-30
  • Contact: NIU Xiaohui

Abstract: Objective To explore the improvement effect of surgical treatment on quality of life of patients with metastatic carcinoma in the pelvis.
Methods A retrospective analyze was carried out on the surgical treatment of 67 patients with metastatic carcinoma in the pelvis from November 1984 to September 2011 in our hospital. The survival data, musculoskeletal tumor society(MSTS), visual analog scale(VAS) and Karnofsky performance scale(KPS) were followed up. The medium overall survival(OS) and scores of MSTS, VAS and KPS were analyzed before and after January 1, 2007. Results All patients were followed for 1-90 months(median: 15.5 months). Thirty-five cases were followed for more than 6 months and 30 cases were followed for more than 12 months. Among 35 patients with more than 6month follow-up, the 5-years overall survival rate was 42.9% and the median OS was 46.0 months. Significant difference was observed among patients with different primary tumors(P<0.05), but not among patients with different age, sex and surgical border(P>0.05). The overall MSTS was 22.9±3.4 and a higher MSTS score was in reconstruction versus nonreconstruction(P<0.05). The postoperative VAS and KPS were superior to those preoperative with statistical significance. The decreased value of VAS,increased value of VAS, MSTS score and median OS after January 1, 2007 were superior to those before January 1, 2007(P<0.05). Conclusion For pelvic metastases, surgical treatment should be given without delay based on the indications for surgery, which can effectively relieve pain, recover activity and improve the life quality of patients.

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