Chinese Clinical Oncology

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Clinical observation of the intensity modulated radiotherapy in cervical stump cancer

XU Hanzi, LU Emei, SUN Zhihua, WU Qiang, ZHANG Xiuming, GONG Zhen.
  

  1. Department of Radiation Oncology,Jiangsu Cancer Hospital, Nanjing 210009, China
  • Received:2014-10-06 Revised:2014-12-25 Online:2015-03-31 Published:2015-03-31

Abstract: Objective To evaluate the efficacy and side effects of the intensity modulated radiotherapy in cervical stump cancer. Methods A retrospective study included 41 patients from January 1994 to December 2013 with cervical stump cancer was performed. Before 2012, 18 cases as control group were received conventional external beam radiotherapy and brachytherapy. Since 2012,23 cases as experimental group were treated with intensity modulated radiotherapy(IMRT) and brachytherapy. The efficacy and complications of two groups were evaluated. Results In the control group,there was 8 cases CR, 6 cases PR, and the response rate was 77.8%, and the decreasing rate of SCC was(61.3±20.4)%. In the experimental group, there was 12 cases CR, 8cases PR, and the response rate was 87.0%, and the decreasing rate of SCC was(75.9±4.3)%. There was 17 patients suffered toxicities including 13 grade 1-2 acute rectum reaction,4 grade 1 bladder reaction the control group, while in the experimental group, only 6 patients suffered grade 1 acute rectum reaction. Conclusion The IMRT and braehytherapy for the patients with cervical stump cancer have better effects and less complications.

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