Chinese Clinical Oncology

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Advance of long non-coding RNA UCA1 in tumors

CHEN Liuwei,WANG Zhaoxia   

  1. Department of Clinical Medicine,the First Medical College of Nanjing Medical University,Nanjing 210029,China
  • Received:2015-08-17 Revised:2015-09-17 Online:2016-01-31 Published:2016-01-31
  • Contact: WANG Zhaoxia

Abstract:

Recently,high expression of long non-coding RNA urothelial carcinoma antigen 1(UCA1)has been found in various human carcinomas(bladder urothelial carcinoma,gastric cancer,hepatocellular carcinoma,ovarian cancer,etc)acting as proto-oncogene. UCA1 is playing an important role in the development and progression of tumors. As a novel biological marker,it is indispensible during the process of diagnosis,therapy and prognosis. In this view,we summarize the latest progress,both domestic and overseas,on the advance of UCA1 in tumor research.

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