Chinese Clinical Oncology

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Clinical diagnosis and treatment of 63 cases of thyroid microcarcinoma

LUAN Yang,CHEN Jian,WANG Kanglei,WANG Wei,ZONG Guangquan, WANG Feng,LIU Xushun   

  1. Department of General Surgery,81 Hospital of PLA,Nanjing 210002,China
  • Received:2016-01-18 Revised:2016-02-25 Online:2016-04-30 Published:2016-04-30

Abstract: Objective To investigate clinical characteristics,diagnosis and surgical treatment for thyroid microcarcinoma. Methods Sixty-three patients with thyroid microcarcinoma from January 2005 to August 2014 were enrolled. The clinical data including diagnosis,surgical treatment,clinicopathological characteristics and follow-up results were reviewed. Results There were 32 cases(50.8%)suspected of micocarcinoma by color Doppler ultrasound before operation. Biopsy by fine-needle aspiration guided by color Doppler ultrasound were performed in 4 cases(6.4%)before operation,and 3(4.8%)of them were confirmed. There were 41 cases(74.6%)confirmed by frozen section pathological diagnosis during operation. Postoperative pathologic diagnosis of 63 cases was papillary carcinoma. Total thyroidectomy was performed in 12 cases. Subtotal thyroidectomy was performed in 17 cases. Lobectomy and isthmectomy for tumor side and subtotal lobectomy for another side were performed in 20 cases. Subtotal lobectomy for tumor side and lobectomy for another side and isthmectomy were performed in 8 cases. Lobectomy and isthmectomy were performed in 4 cases. Lobectomy and isthmectomy for tumor side and partial lobectomy for another side were performed in 2 cases. Functional neck dissection was performed in 2 cases. Central district dissection was performed in 4 cases. Follow-up was ranged from 1 year and 3 months to 10 years and 11 months,and 1 case lost contact in our survey;62 patients were alive,among them 1 case was found recurred after surgery and total thyroidectomy was performed then. Conclusion The prognosis of most of thyroid microcarcinoma is satisfied by surgical treatment,but partially is aggressive. Individualized treatment should be emphasized.

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