Chinese Clinical Oncology

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Strategies and advances in immunotherapy of non-small cell lung cancer

LU Chang, WANG Aman, LI Ying, Ning Zhen, LIU Jiwei.

  

  1. Department of Oncology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China
  • Received:2016-01-08 Revised:2016-02-17 Online:2016-05-31 Published:2016-05-31
  • Contact: LIU Jiwei

Abstract: Non-small cell lung cancer(NSCLC) is a highly prevalent and aggressive disease. In recent years, the long time survival rate of patients with advanced NSCLC remains low despite of advances in surgery, irradiation, chemotherapy and targeted therapy. The aim of immunotherapy is to specifically enhance the immune response directed to the tumor. Many trials have addressed the role of novel immunotherapeutic agents, such as checkpoint inhibitors and antigenspecific tumour vaccines, which has made breakthrough progress in NSCLC. Immunotherapy will be a fundamentally new concept for the treatment of NSCLC.

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