Abstract: Cancer cachexia is a cancerinduced multifactor complex syndrome. About 50％80％ of patients with advanced malignant tumors suffer from cancer cachexia， which counteracts effect of antitumor therapy， reduces the quality and duration of life. The mechanism of this metabolic disorder caused by tumors， is very complicated because of its serious influence on multiorgan. As a result， the evaluation and staging of its severity become difficult things. Furthermore， the intervention means to ameliorate cancer cachexia are limited at present while so much disagreement of views on treatment exists. The individualized， multidisciplinary， multimodal therapies are now advocated in clinical practice. In this paper， we shall review the progress in researches from the aspects of mechanism， evaluation and clinical medication of cancer cachexia.

Key words: Cancer cachexia, Pathogenesis, Stage evaluation, Intervention and medication