临床肿瘤学杂志

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EGFR-TKI与化疗药物在晚期非小细胞肺癌中最佳联合方式的探讨

寻琛1,王琳1,边劲2   

  1. 1 解放军八一医院全军肿瘤中心内科 2 安徽医科大学南京解放军八一医院临床学院
  • 收稿日期:2012-09-03 修回日期:2012-10-10 出版日期:2012-12-31 发布日期:2012-12-31
  • 通讯作者: 王琳

Promising combinations of EGFR-TKI and chemotherapy in advanced nonsmall cell lung cancer

XUN Chen, WANG Lin, BIAN Jing   

  1. 81st Hospital of PLA
  • Received:2012-09-03 Revised:2012-10-10 Online:2012-12-31 Published:2012-12-31
  • Contact: WANG Lin

摘要: 表皮生长因子受体酪氨酸激酶抑制剂(EGFR-TKI)已成为晚期非小细胞肺癌(NSCLC)的治疗药物之一。如何将EGFR-TKI与传统化疗药物合理组合,从而达到更佳的疗效日益受到人们关注。本文拟将目前研究较多的化疗药物与EGFRTKI的组合进行综述,梳理可能的最佳联合方式。

Abstract: Epidermal growth factor receptor tyrosine kinase inhibitor(EGFR-TKI) has been one of the most important treatments for advanced non-small cell lung cancer(NSCLC). How to effectively combine EGFR-TKI with traditional chemotherapy, so as to get a better efficacy, has been given an increasing attention. The aim of this review is to introduce some combinations of EGFRTKI and chemotherapy, try to find the best combination.

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