27例眼附属器淋巴瘤的临床病理特征分析

临床肿瘤学杂志

27例眼附属器淋巴瘤的临床病理特征分析

朱静^1，2，秦叔逵¹，施毅²，王琳¹，陈映霞¹，华海清¹，刘秀峰¹，李桂梅³，张志强⁴

1 解放军八一医院全军肿瘤中心 2 南京大学医学院南京军区南京总医院呼吸内科 3 解放军八一医院病理科 4 解放军八一医院眼科

收稿日期:2014-08-06 修回日期:2014-09-25 出版日期:2014-11-30 发布日期:2014-11-30
通讯作者: 秦叔逵,施毅

Clinical and pathological features of ocular adnexal lymphoma in 27 patients

ZHU Jing，QIN Shukui，SHI Yi，WANG Lin，CHEN Yingxia，HUA Haiqing，LIU Xiufeng，LI Guimei，ZHANG Zhiqiang.

Department of Respiratory Medicine, Medical School, Nanjing University, Nanjing General Hospital of Nanjing Military Command,PLA Cancer Center, Bayi Hospital

Received:2014-08-06 Revised:2014-09-25 Online:2014-11-30 Published:2014-11-30
Contact: QIN Shukui,SHI Yi

摘要/Abstract

摘要： 目的探讨国人眼附属器淋巴瘤的临床病理特征。方法回顾性分析解放军八一医院全军肿瘤中心1990年1月至2013年12月收治的27例经病理组织学检查确诊为眼附属器淋巴瘤患者的临床及病理学特征。结果 27例患者均为非霍奇金淋巴瘤，原发于眼部者25例，其他部位淋巴瘤累及眼部者2例。病理分型：NK/T细胞淋巴瘤2例；B细胞淋巴瘤25例，其中包括黏膜相关淋巴组织（MALT）淋巴瘤13例，淋巴浆细胞性淋巴瘤（LPL）4例，套细胞淋巴瘤（MCL）3例，小淋巴细胞性淋巴瘤（SLL）2例，髓外浆细胞瘤（EMP）3例。13例既往诊断为小B细胞淋巴瘤，经免疫组织化学染色，确诊为MALT淋巴瘤8例、MCL 3例和SLL 2例。结论眼附属器淋巴瘤的病理诊断分类多样，明确诊断可以为患者治疗方案的选择和判断预后提供更合理的建议。

Abstract: Objective To explore the clinical manifestations and pathological features of ocular adnexal lymphoma. Methods The clinical and pathological information of 27 patients diagnosed as ocular adnexal lymphoma in 81 Hospital of PLA by pathological examination from January 1990 to December 2013 were collected， and the pathological features of the disease were analyzed retrospectively. Results The lesions were limited to the orbital area in 25 cases and the rest 2 cases were secondary to the lymphoma of other organs. The pathological diagnosis in all the cases was non-Hodgkin's lymphoma， of which T cell in 2 cases and B cell lymphoma in 25 cases including mucosaassociated lymphoid tissue（MALT） lymphoma 13 cases， lymphoplasmacytic lymphoma（LPL） 4 cases， mantle cell lymphoma（MCL） 3 cases，small lymphocytic lymphoma（SLL）2 cases，extramedullary plasmacytoma（EMP） 3 cases. There were 13 cases originally diagnozed as small B cell lymphoma. They were clearly diagnozed as 8 MALT lymphoma, 3 MCL and 2 SLL by immunohistochemical staining. Conclusion Clear classification can provide more useful suggestions about the choice of treatment and prognosis for the patients.

朱静^1，2，秦叔逵¹，施毅²，王琳¹，陈映霞¹，华海清¹，刘秀峰¹，李桂梅³，张志强⁴. 27例眼附属器淋巴瘤的临床病理特征分析[J]. 临床肿瘤学杂志, 2014, 19(11): 1024-.

ZHU Jing，QIN Shukui，SHI Yi，WANG Lin，CHEN Yingxia，HUA Haiqing，LIU Xiufeng，LI Guimei，ZHANG Zhiqiang.. Clinical and pathological features of ocular adnexal lymphoma in 27 patients[J]. Chinese Clinical Oncology, 2014, 19(11): 1024-.

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