Abstract: Objective To study the clinical and pathological characteristics of cardiac papillary fibroelastoma which could facilitate the diagnosis and treatment. Methods Six cases of cardiac papillary fibroelastoma which were treated in our hospital in the recent 10 years were reviewed retrospectively. All the cases of cardiac papillary fibroelastoma were stained routinely by HE and an elastic stain. Results The typical tumor showed the appearance of sea anemone. It was coated by a layer of endothelial cells， and fine papillary branches can be observed under a microscope. There were some elastic fibers in the tumor. The patients were followed for 3 months to 8 years， and no recurrence was observed. Conclusion Cardiac papillary fibroelastomas is rare， and it is a primary benign tumor of the heart valves. The clinical manifestations of cardiac papillary fibroelastoma are not characteristic， it is hard to diagnose according to clinical manifestations. But the tumor has typical histomorphological features， it can be diagnosed by pathological examination.