Abstract: Bladder cancer is the most common malignant tumor of urinary system， which has taken the first place in the incidence of urinary reproductive system tumor in our country. The method of bladder hyperthermic perfusion chemotherapy was proved to be a useful and effective method in the prevention of superficial bladder cancer recurrence of patients with superficial bladder cancer after transurethral resection. This article will focus on the clinical applications of bladder hyperthermic perfusion chemotherapy in the bladder cancer.