Abstract: Objective To explore the rescue method of nasopharyngeal bleeding after re-course radiotherapy of nasopharyngeal cancer. Methods Nine patients with epistaxis after radiotherapy of nasopharyngeal cancer therapy were retrospectively analyzed. All the patient received pre- and post-nostril packing hemostasis. Results In the course of rescue, 2 cases died due to suffocation and hemorrhagic shock, repectively. Seven cases survived from bilateral carotid artery angiogaphy. Conclusion Filling up pre- and post-nostril with endovascular embolization combination therapy can improve the success rate of epistaxis after nasopharyngeal cancer recourse radiotherapy, and worth promoting.