Abstract: ObjectiveTo explore the diagnostic value of color doppler ultrasound for papillary thyroid carcinoma（PTC）. Methods One hundred and fifteen cases with PTC and 129 cases with thyroid benign mass who were confirmed by pathology were analyzed comparatively with color doppler ultrasound. The chisquare test and multivariate logistic regression analysis were used to identify the prognostic factors. Results The sensitivity and specificity of ultrasound for the diagnosis of PTC was 82.07％ and 86.75％. PTC could be diagnosed according to features detected by ultrasound，including mass shape， boundary， echo， calcification and so on. The sensitivity of boundary and echo was 87.20％ and 84.80％；and the specificity of aspect ratio and microcalcification was 92.59％ and 86.75％. The result of χ2 analysis was meaningful ultrasonic features including mass shape， boundary， echo and microcalcification. The result of Logistic regression analysis was echo and microcalcification with significant differences in the prognostic factors in PTC. The odd ratio（OR） of echo was 3.13（95％CI： 1.58-6.19，P=0.001）.The OR of microcalcification was 2.03（95％CI： 1.19-3.48， P=0.02）.
Conclusion Two dimensional ultrasound is basic examination in diagnosis of PTC， microcalcification and low echoes in high frequency ultrasonography may be an important diagnostic indicator for PTC， which can be useful in differentiating PTC from benign thyroid mass.