临床肿瘤学杂志
• 综述与讲座 • 上一篇 下一篇
杨芳,管晓翔
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YANG Fang, GUAN Xiaoxiang.
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摘要: microRNA(miRNA)是近年来发现的一种可以调控基因表达的单链小分子RNA,其表达异常或突变被认为与多种肿瘤的发生、发展有关。有研究表明,miRNA在三阴性乳腺癌中扮演着重要角色,这将为后者的治疗提供新思路。本文就miRNA作为一种新的分子标志物在三阴性乳腺癌中的研究进展作一综述。【关键词】miRNA;三阴性乳腺癌;分子标志物
Abstract: MicroRNAs (miRNAs) are recently discovered, small singlestrand RNA molecules that can regulate gene expression, and the abnormal expression or mutation in miRNAs are considered to be associated with the initiation and progression of a variety of tumors. It has been identified that miRNAs play a crucial role in triple negative breast cancer, providing a novel possible therapeutic application. In this review, we will provide an overview of the application of miRNAs in triple negative breast cancer.
杨芳,管晓翔. MicroRNA在三阴性乳腺癌发生发展中的作用[J]. 临床肿瘤学杂志, 2014, 19(10): 950-.
YANG Fang, GUAN Xiaoxiang.. Progression on the role of microRNAs in the initiation and progression of triple negative breast cancer[J]. Chinese Clinical Oncology, 2014, 19(10): 950-.
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http://manu65.magtech.com.cn/Jwk3_lczlxzz/CN/Y2014/V19/I10/950
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