临床肿瘤学杂志

• 综述与讲座 • 上一篇    下一篇

胃神经内分泌肿瘤的诊断和治疗

刘 丹1,2,沈 琳1,2,陆 明1,2   

  1. 1 100142 北京 北京大学临床肿瘤学院 北京肿瘤医院暨北京市肿瘤防治研究所消化道肿瘤多学科协作组 2 100142 恶性肿瘤发病机制及转化研究教育部重点实验室
  • 收稿日期:2014-10-22 修回日期:2015-03-27 出版日期:2015-06-30 发布日期:2015-06-30
  • 通讯作者: 陆 明

Diagnosis and treatment for gastric neuroendocrine tumors

LIU Dan, SHEN Lin, LU Ming.

  

  1. Multidisciplinary Collaboration Group, Pecking University School of Oncology, Beijing Cancer Hospital & Institute, Beijing 100142, China
  • Received:2014-10-22 Revised:2015-03-27 Online:2015-06-30 Published:2015-06-30
  • Contact: LU Ming

摘要: 胃神经内分泌肿瘤(G-NETs)是指来源于胃上皮及类肠嗜铬(ECL)细胞等神经内分泌细胞相关的肿瘤,占胃原发肿瘤一小部分,故长期以来对其认识局限,诊疗缺乏统一标准。但近年来G-NETs发病率较前明显升高,对其认识逐渐加深,临床根据G-NETs分化程度、与高胃泌素血症相关与否分为4个亚型,并针对不同亚型进行治疗。本文就近年来有关G-NETs流行病学、临床表现、诊断标准、治疗方法等最新进展做一综述,以期为G-NETs的诊疗提供参考。

Abstract: Gastric neuroendocrine tumors(G-NETs) arise in enterochromaffin-like(ECL) cells, which only account for a small part of gastric tumors. People have been less focused on them, so that the diagnosis and treatment of G-NETs are lack of acknowledged guidelines. However, with the increasing incidence, there is more deeply acknowledge in this field. In clinical, G-NETs are compromised of 4 subtypes according to differentiation and the relationship with hypergastrinemia. In the current review, we summarize the pathology, clinical characteristics, which aimed at treatment of it.

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