Abstract: Objective To explore the efficacy and safety of intensity modulated radiotherapy（IMRT） and three dimensional conformal radiotherapy（3DCRT） in cervical cancer patients after the surgery. Methods IMRT and 3DCRT plans were designed for 60 cervical cancer patients after the surgery. Patients were randomly assigned to IMRT group and 3DCRT group. The dose distribution of planning target volume（PTV） and organ at risk （OAR） were evaluated. And the acute and chronic radiation injury， 3 years overall survival （OS） were compared between two groups. Results The conformation index （CI）， relative dose homogeneity index （HI） of PTV were significant different between two groups （P＜0.05）. Compared with 3DCRT group， V10， V20， V30， V40 and V45of anterior bladder wall and the V20， V30， V40 and V45of posterior rectal wall were significant lower in IMRT group （P＜0.05）. And the acute and chronic radiation injury of rectal and bladder were significant slighter in IMRT group. There was no difference in 3-year survival rates between two groups. Conclusion IMRT was superior to 3DCRT in CI， HI of PTV and the protection of the anterior bladder wall and the posterior rectal wall.