Abstract: Objective To investigate the diagnostic value of contrast enhanced ultrasound（CEUS） and contrast enhanced X-ray computed tomography（CECT） in the diagnosis of hepatocellular carcinoma with different tumor sizes. Methods The data of 197 cases of hepatocellular carcinoma of our hospital from June 2013 to June 2016 were analyzed retrospectively. The nidus of all patients were single，in which the maximum diameter was 3.0-5.0 cm as medium hepatocellular carcinoma group（A）， and the others was in nonmedium hepatocellular carcinoma group（B）. CEUS and CECT were done in all the 197 patients, including 96 patients in group A, and the other 101 patients in group B. The χ2 test was used to compare the CEUS and CECT in the diagnosis of hepatocellular carcinoma with different sizes.
ResultsThe area under the curve of CEUS and CECT in the 197 cases were 0.774 and 0.706 respectively， whose difference was not statistically significant（P＞0.05）. However， in group A， the specificity by CEUS was 80.6％-85.8％， and the sensitivity was 73.2％-91.6％；while the specificity by CECT was 65.1％-77.2％， and the sensitivity was 63.2％-85.3％. The accuracy rates of CEUS and CECT in group B were 92.1% and 91.1%（P＞0.05）. The accuracy rates of CEUS and CECT in group A were 97.9% and 89.6%（P＜0.05）. Conclusion For the measurement of the size of liver cancer lesions, especially in the liver cancer patients with medium size liver lessions, preoperative selection of CEUS has higher application value.