临床肿瘤学杂志

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腹腔镜在早期宫颈癌根治术中的应用效果评价

陈菊1,2,李力1, 张洁清1, 宋红林1, 王鹤1, 姚德生1, 潘忠勉1, 阳志军1   

  1. 1 广西医科大学附属肿瘤医院妇瘤科 区域性高发肿瘤早期防治研究教育部重点实验室2 广西科技大学第一附属医院妇产科
  • 收稿日期:2016-11-21 修回日期:2017-04-08 出版日期:2017-07-31 发布日期:2017-07-31
  • 通讯作者: 阳志军

Application of laparoscopic radical hysterectomy for earlystage cervical cancer

CHEN Ju, LI Li, ZHANG Jieqing, SONG Honglin, WANG He, YAO Desheng, PAN Zhongmian, YANG Zhijun.
  

  1. Department of Gynecologic Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Key Laboratory of Early Prevention and Treatment of Regional High Risk of Tumor
  • Received:2016-11-21 Revised:2017-04-08 Online:2017-07-31 Published:2017-07-31
  • Contact: YANG Zhijun

摘要:

目的 探讨腹腔镜手术治疗早期宫颈癌的可行性、安全性及临床价值。方法 收集2009年1月至2014年12月在广西医科大学附属肿瘤医院妇瘤科行宫颈癌根治术的623例早期宫颈癌患者的病历资料,按手术方式分组:腹腔镜组374例,开腹组249例。回顾性分析两组患者的基本情况、手术时间、术中出血量、术中淋巴结切除数目、宫旁组织及阴道切除长度及手术并发症。结果 腹腔镜手术组成功实施368例,成功率98.40%(368/374),中转开腹6例,中转开腹率1.60% (6/374)。腹腔镜组在手术时间、术中出血量、术后下床活动时间、肛门排气时间均优于开腹组,差异均有统计学意义(P<0.05),而两组淋巴结切除数、宫旁组织和阴道切除长度比较,差异均无统计学意义(P>0.05)。在术中及术后并发症方面,除尿潴留外,两组差异均无统计学意义(P>0.05)。结论 腹腔镜下宫颈癌根治术较传统开腹手术创伤小、术中出血量少、术后并发症少及术后恢复快,是治疗早期宫颈癌有效、安全的方法。

Abstract: Objective To investigate the feasibility, superiority and clinical application of laparoscopic radical hysterectomy for early-stage cervical cancer.
Methods Clinical dates of 623 cases of earlystage cervical cancer treated with radical hysterectomy combined with pelvic lymphadenectomy or paraaortic lymphadenectomy from January, 2009 to December, 2014 in the Department of Gynecologic Oncology of Affiliated Tumor Hospital of Guangxi Medical University were analyzed. According to the surgical approach, they were divided into laparoscopic surgery group(374 cases)and transabdominal surgery group(249 cases). A retrospectively analysis was carried out to compare the basic situations, operation time, intraoperative blood loss, number of resected lymph nodes, length of vagina and parametrium removal and incidences of complications. Results 368 cases with laparoscopic surgery were performed successfully, the rate of success reached 98.40%(368/374),6 cases were converted to open surgery, and the rate of conversion to laparotomy reached 1.60%(6/374). The operation time, intraoperative blood loss, ambulation time and recovery time of intestines in laparoscopic surgery group were better than those in transabdominal group, and the difference was statistically significant(P<0.05). While the number of resected lymph nodes,length of vagina and parametrium removal of two groups were not statistically significant(P>0.05). In the intraoperative and postoperative complications, except for urinary retention, there was no significant difference between the two groups(P>0.05). Conclusion There were several advantages including minimal invasive, less blood loss and less postoperative complications and quicker recovery in laparoscopic radical hysterectomy,when compared with traditional transabdominal surgery. It is effective and safe for earlystage cervical cancer.

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