Chinese Clinical Oncology

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Progress on gastric cancer stem cell research

CHEN Jianxin,CHEN Xiong,OUYANG Xuenong

  

  1. Clinical Institute of Fuzhou,General Hospital,Fujian Medical University, Fuzhou 350025,China
  • Received:2013-05-25 Revised:2013-06-08 Online:2013-10-31 Published:2013-10-31

Abstract: With the progress on the basic study of malignant tumor,the existence of cancer stem cell has been confirmed by numerous researches and well accepted. So far, numbers of cancer stem cells including hematological malignancy and solid tumors have been isolated and identified. As one of the top morbidity and mortality rate cancers, the gastric cancer cells which obtain the characteristics of cancer stem cells have been separated. Because of the consensus of the specific marker of gastric cancer cells has not been reached,the marker has not been confirmed yet. So far,a great number of relative researches have reported different gastric cancer stem-like cells,most of which interestingly possess the characteristics of cancer stem cells including the ability of plate clone formation, differentiation and tumorigenicity. The passage will summarize the researches on gastric cancer stem cells in recent years.

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