Chinese Clinical Oncology
• 综述与讲座 • Previous Articles Next Articles
ZHOU Yan,DONG Wen,MA Jin'an.
Received:
Revised:
Online:
Published:
Abstract: Cellular immune system plays a very important role in the body's immune response to malignant tumor. Cytotoxic T lymphocyteassociated antigen 4(CTLA-4) involves in the induction and maintenance of T cell immune tolerance through inhibiting T cell activity,so the monoclonal antibody which blocks the CTLA-4 can stimulate the proliferation of immune cells,thereby enhances the body's immune response to the tumor. This paper mainly reviews the research progresses about CTLA-4 monoclonal antibody drugs(ipilimumab and tremelimumab) in recent years and the clinical application progress of them.
ZHOU Yan,DONG Wen,MA Jin'an.. CTLA-4 monoclonal antibodytargeted passive immunotherapy for tumor[J].Chinese Clinical Oncology, 2013, 18(3): 268-.
0 / / Recommend
Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks
URL: http://manu65.magtech.com.cn/Jwk3_lczlxzz/EN/
http://manu65.magtech.com.cn/Jwk3_lczlxzz/EN/Y2013/V18/I3/268
Cited