Chinese Clinical Oncology

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Clinicopathological features of primary hepatic malignant vascular tumors: A analysis on 41 cases

ZHAO Qian, LIU Haiping, XIAN Zhihong, LU Xinyuan, DONG Hui, CONG Wenming.   

  1. Department of Pathology, Eastern Hepatobilliary Surgery Hospital, Second Millitary Medical University
  • Received:2013-03-13 Revised:2013-05-13 Online:2013-08-31 Published:2013-08-31
  • Contact: CONG Wenming

Abstract: Objective To investigate the clinicopathological and prognostic features of primary hepatic malignant vascular tumor(PHMVT). Methods Forty-one patients with PHMVT who underwent surgical resection and confirmed by pathology in our hospital from January 1982 to December 2012 were analyzed for their clinical manifestations, pathological characteristics and prognosis. Results Of the 41 patients, pathological classification contained 19 EHE(46.3%),14 PHA(34.1%),5 IHE(12.2%)and 3 MHP(7.3%). The average diameters of the 4 kinds tumor were followed by 4.9cm(1.2-6.3 cm), 8.3cm(3.0-14.0 cm), 3.8cm(1.2-6.3cm) and 7.8cm(2.1-13.0cm). Immunohistochemistry showed all of 41 cases expressed Vimentin, CD34 or factor Ⅷ. EHE patients showed better postoperative survival than PHA patients(87 months vs. 12 months, P<0.05). Two patients with MHP who had complete followup data, one patient relapsed at the 84th month postoperative, another died of disease in 43 months after operation. Patients with IHE recovered well with no recurrence after operation. Conclusion The prognosis of patients with PHMVT is associated with pathological types; and the malignant degree of PHMVT are in sequence of PHA>MHP>EHE>IHE.

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