ZHANG Yonghui WANG Yong SUN Xiaohu CHEN Zujin Clinical analysis on individualized breast-conserving surgery for 165 patients with breast cancer

Chinese Clinical Oncology

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Clinical analysis on individualized breast-conserving surgery for 165 patients with breast cancer

ZHANG Yonghui WANG Yong SUN Xiaohu CHEN Zujin

  1. the First Department of Breast Oncology, Cancer hospital of Tianjin Medical University, key Laboratory of Breast Cancer Prevention and Therapy of Ministry of Education, Tianjin 300060, China
  • Received:2015-08-03 Revised:2015-12-24 Online:2016-03-30 Published:2016-03-30

Abstract:

Objective To investigate the reasonable selection and application of standard breast-conserving surgery and oncoplastic breast-conserving surgery

for breast cancer. Methods A total of 165 patients that underwent breast-conserving surgery were divided into two groups: group of standard breast-conserving surgery(n=64) and group of oncoplastic breast-conserving surgery(n=101). The tumor features, surgical procedures, postoperative complications and cosmetic outcome of the operation were compared between both groups. Results There was no statistical difference concerning the postoperative complications, cosmetic outcome, recurrence and metastasis between the 64 cases of standard breast-conserving surgery group and the 101 cases of oncoplastic breast-conserving surgery group. There was statistical difference concerning the location distribution of tumor, weight of the surgical specimen, breast size, size or scope of primary tumor and the neoadjuvant chemotherapy between both groups. The weight of the surgical specimen was greater in oncoplastic breast-conserving surgery group than that in standard breast-conserving surgery group. The primary tumor applying oncoplastic breast-conserving surgery was more in the central zone, the upper inner quadrant and the lower quadrant. ConclusionThe individualized breast-conserving model can better insure the breast cosmetic outcome of the operation with staging dynamic evaluation and concrete analysis of concrete conditions to the breast-conserving patients. The oncoplastic surgery makes it possible to excise more tissues in breast-conserving surgery, so as to ensure the negative margin and increase the success rate of the breast-conserving surgery, thus reducing the unnecessary mastectomy and breast reconstruction. It deserves further clinical research and promotion.

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