Chinese Clinical Oncology

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Prognostic value of tumor deposit in gastric cancer patients

JIANG Huiqin, LI Qian, LI Wei, LI Hong, YU Yiyi, LIU Tianshu.
  

  1. Department of Medical Oncology, Zhongshan Hospital, Fudan University, Shanghai 200032,China
  • Received:2017-04-13 Revised:2017-08-08 Online:2017-09-30 Published:2017-09-30
  • Contact: LIU Tianshu

Abstract: Objective To examine the prognostic values of tumor deposits (TDs) in gastric cancer. Methods The patients underwent radical gastrectomy and histopathologically diagnosed as gastric cancer from April 2015 to January 2016 were involved. The relationship between the status of TDs and clinicopathological features of gastric cancer was analyzed. The 1-year disease-free survival (DFS) rate was calculated. Results The positive rate of TDs in 137 cases of gastric cancer was 24.8%. Univariate analysis showed that T/N stage and neural/vascular invasion were related to the positive expression of TDs. The 1-year DFS rates of the TD positive group and TD negative group were 59% and 85%, respectively. In the Ⅰ/Ⅱ stage, the 1-year DFS rates of the TD positive group and TD negative group were 40% and 91%, respectively. Conclusion The TD status was positively correlated with T/N stage and nerve/vascular invasion after radical gastrectomy. TD positive was a poor prognostic factor, indicatingearly relapse after radical gastrectomy. The prognostic value of TD was more significant in stage Ⅰ/Ⅱ gastric cancer patients.

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