Abstract:

Objective To investigate the eventbased prospective memory （EBPM） and timebased prospective memory （TBPM） disorders associated with chemotherapyinduced cognitive impairment in patients with breast cancer. Methods Twentyseven cases with breast cancer who underwent adjuvantchemotherapy after operation，and 30 healthy women with matched age and education level were administered with a neuropsychological battery of tests including EBPM and TBPM tasks. Results The EBPM score of breast cancer patients and healthy controls were 1.11±1.09 and 2.23±0.77， with significant differences（P＜0.001）.The TBPM score of breast cancer patients and healthy controls were 4.33±1.24 and 483±1.09（P＞0.05）. Conclusion Breast cancer patients who undergo adjuvant chemotherapy show deficits in EBPM， but not in TBPM.