Abstract:

Objective To explore the value of virtual touch tissue quantification（VTQ） in the diagnosis of breast fibroadenoma. Methods One hundred sixtysix cases with 198 nodules of breast fibroadenoma confirmed by pathology underwent routine preoperative ultrasound and VTQ examination. The valid VTQ value was recorded and ROC curve was drawn using the average shear wave velocity（Vm） as to seek the diagnostic cutoff. Results Among the 198 nodules， VTQ value of 25 nodules was absent. We found that the Vm could be used to diagnosis the breast fibroadenoma with the area under the curve greater than 0.80. The sensitivity， specificity and accuracy of Vm in distinguishing fibroadenoma were 86.1％， 70.2％， 86.3％ when using 2.25 m／s as the cutoff. The blood flow signal of breast fibroadenoma had some affection on the VTQ value. The VTQ of fibroadenoma without blood flow signal was higher than that of fibroadenoma with blood flow signal（P＜0.01）. There were no significant difference of VTQ value among breast fibroadenoma with different diameters and different depths（P＞0.05）.
Conclusion VTQ has great value in the diagnosis of breast fibroadenoma.