Abstract: ObjectiveTo explore the efficacy of octreotide acetate （OA） injection in the enhancement of colorectal cancer（CRC） patients recovery following laparoscopic surgery. 
MethodsFrom October 2014 to September 2016， CRC patients who underwent laparoscopic surgery and did not indwell nasogastric tubes after surgery were divided into 2 groups： OA group （103 patients）， who received routine therapy plus OA injection at a dose of 02 mg ih q8h for 3 days and control group （51 patients） subjected only to routine therapy. Patients of the two groups were observed for nasopharynx discomfort， abdominal distention， nausea， vomiting， intestinal obstruction， pulmonary infection， anastomotic leakage， rein dwelling nasogastric tubes， the first passage of flatus and hospital stay. 
ResultsFive patients suffered from postoperative abdominal distention in the OA group， less than 9 patients in the control group （P＜005）. Eight patients suffered from postoperative nausea and vomiting in the OA group， less than 10 patients in the control group（P＜005）. Five patients suffered from postoperative nasopharynx discomfort in the OA group，similar with 3 patients in the control group（P＞005）. Three patients in the OA group and 3 patients in the control group reined dwelling nasogastric tubes because of intestinal obstruction or severe nausea and vomiting， and there was no statistic difference significantly between two groups（P＞005）. In addition， postoperative intestinal obstruction， pulmonary infection， anastomotic leakage， the first passage of flatus and hospital stay remained unchanged between the two groups （P＞005）. 
ConclusionOA injection can effectively reduce abdominal distention and nausea and vomiting after laparoscopic CRC surgery, and can be used safely after operation.

Key words: Colorectal cancer （CRC）, Octreotide acetate （OA） injection, Laparoscopic surgery, Enhanced recovery