Abstract:  

ObjectiveTo investigate the safety and effectiveness of enhanced recovery after surgery （ERAS） in perioperative period of colorectal cancer and the influence on postoperative nutritional status and immune.

Methods  A total of 61 patients with colorectal cancer from August 2015 to January 2017 were randomly divided into two groups. Thirty-one cases in fasttrack （FT） group were given perioperative management of ERAS and 30 cases in routine control （CT） group were given the conventional treatment. The albumin， prealbumin， transferrin， IgG， IgA， IgM， C-reactive protein， peripheral blood glucose， postoperative initial anal exhaust time， length of hospital stay， hospitalization cost and postoperative complications were compared between the two groups. Results  A total of 54 patients completed the experiment, with 27 patients in each group. Compared with CT group， the albumin， transferrin and IgG were significantly higher in FT group at 1， 3 and 5 days after surgery（P＜0.05）. The postoperative initial anal exhaust time and the length of hospital stay was shorter in FT group compared with CT group （P＜0.05）. The hospitalization costs of FT group and CT group was （20.3±1.2） and （27.6±0.9） thousand yuan， respectively （P＜0.05）. There was no significant difference in Creactive protein， peripheral blood glucose， IgA， IgM and post-operative complications between the two groups （P＞0.05）. Conclusion  ERAS is safe and effective for patients with colorectal cancer， and it has positive effect on postoperative nutritional status and immune of patients.

Key words:  , Colorectal cancer">Colorectal cancer')">">, Enhanced recovery after surgery（ERAS）, Perioperative period