临床肿瘤学杂志

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人端粒酶逆转录酶在宫颈癌及其癌前病变中的研究进展

李雯茹,赵 欣   

  1. 200060 上海 上海市普陀区妇婴保健院妇产科
  • 收稿日期:2016-07-04 修回日期:2016-10-11 出版日期:2017-01-30 发布日期:2017-01-30

Progression on human telomerase reverse transcriptase in cervical cancer and cervical intraepithelial neoplasia

LI Wenru, ZHAO Xin.
  

  1. Department of Gynecology and Obstetrics, Putuo District Maternal Children Health Hospital, Shanghai 200060, China
  • Received:2016-07-04 Revised:2016-10-11 Online:2017-01-30 Published:2017-01-30

摘要: 人端粒酶逆转录酶(hTERT)与癌症的发生发展息息相关。hTERT在宫颈癌及其癌前病变中的作用也已被广泛研究,主要涉及hTERT表达变化与宫颈癌前病变程度的关系以及hTERT表达水平作为宫颈癌诊断和预后的可行性等方面。hTERT在宫颈癌的诊断、预后及治疗中具有极为重要的临床价值。

Abstract: Human telomerase reverse transcriptase (hTERT) is closely related to the occurrence and development of cancer. The role of hTERT in cervical cancer and precancerous lesions has been widely studied, mainly involving the relationship of the change of hTERT expression and the degree of precancerous lesions and the feasibility of the expression of hTERT as the diagnosis and prognosis of cervical cancer, etc. hTERT plays an important role in the diagnosis, prognosis and treatment of cervical cancer.

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