Abstract: ObjectiveTo investigate the clinical characteristics and treatment strategies of the Ewings sarcoma family tumor （ESFT） in the trunk axis. 
MethodsFrom January 2008 to May 2017， 67 cases with complete followup data were selected from 79 patients with localized ESFT in the trunk axis in Affiliated Tumor Hospital of Xinjiang Medical University. According to the treatment， 67 cases were divided into comprehensive therapy group （n=39； including 15 cases of chemotherapy+surgery+radiotherapy， 12 cases of chemotherapy+surgery and 12 cases of chemotherapy+radiotherapy） and simple therapy group （n=28； including 10 cases of chemotherapy， 12 cases of surgery and 6 cases of radiotherapy）. The shortterm efficacy was evaluated by RECIST 11， and longterm survival was analyzed based on followup data. 
ResultsThe effective rate of the comprehensive therapy group was 769％ （30／39）， higher than 500％ （14／28） of the simple therapy group， and the difference was statistically significant （P＜005）. The median overall survival （OS） and eventfree survival （EFS） in the comprehensive therapy group were 570 months and 360 months， better than 190 months and 80 months of the simple therapy group （P＜005）. Among the 39 patients with comprehensive treatment， the effective rate， median OS and EFS were 815％ （22／27）， 480 months and 320 months in 27 cases receiving surgery+radiotherapy+chemotherapy or surgery+radiotherapy， all higher than 667％ （8／12）， 380 months and 235 months in 12 cases receiving radiotherapy+chemotherapy （P＜005）. Among the 39 cases of comprehensive treatment， the effective rate of 24 patients receiving adriamycin combined with ifosfamide （ADM+IFO） regime was 625％ （15／24）， similar with 733％ （11／15） of the remaining 15 patients （nonADM+IFO） （P＞005）. The median OS and EFS of 24 patients receiving ADM+IFO regime were both ＞640 months， similar with 580 months and 340 months of other 15 patients （P＞005）. 
ConclusionComprehensive therapy can improve the efficacy and survival of patients with ESFT in the central axis of the trunk. Chemotherapy and surgery combined with radiotherapy are superior to chemotherapy combined with radiotherapy in the treatment and survival.

Key words: Ewings sarcoma family tumor, Comprehensive treatment, Curative effect analysis, Prognosis