Abstract: The intestinal microflora is composed of symbiotic bacteria and other microorganisms living in the intestinal epithelium of the host. They influence a lot of physiological functions， including homeostasis maintenance of intestinal epithelial barrier and regulations of metabolism， inflammation and immunity. Moreover， intestinal microflora is also involved in the cancer occurrence， progression and metastasis. Intestinal microflora can affect the bodys response to cancer therapies and sensitivity to side effects. In the treatment of cancer， intestinal microflora is closely related to surgery， chemotherapy， radiotherapy and immunotherapy， and it may become one of the frontiers of precise medical treatment and personalized medical treatment. This article reviews the progress of intestinal microflora in cancer therapy.

Key words: Gut microflora, Cancer therapy, Surgery, Chemotherapy, Radiotherapy, Immunotherapy